THE GENETIC CONTROL OF ANTIBODY SPECIFICITY
نویسندگان
چکیده
منابع مشابه
The Genetic Control of Antibody Specificity
The immune response to a synthetic polypeptide built on multichain polyproline, poly-L-(Tyr,Glu)-poly-L-Pro-poly-L-Lys [(T,G)-Pro--L], in the offspring of a cross between DBA/1 and SJL mice is under a genetic control superficially similar to the one operating for the immune response to a similar synthetic polypeptide built on multichain polyalanine, poly-L-(Tyr,Glu)-poly-D,L-Ala-poly-L-Lys [(T,...
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CBA and C57 mice were tested for their ability to make an immune response to a related series of branched, multichain synthetic polypeptide antigens in which the antigenic determinants on the amino termini of the branched side chains were systematically varied. Neither strain responded to the polyglutamic acid determinant. Both strains responded well and equally to the poly(phenylalanine, gluta...
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Biology of the Antibody Specificity
From the Department of Dermatology, University of Cincinnati College of Medicine. Reprint requests: Diya F. Mutasim, MD, Professor and Chairman, Department of Dermatology, University of Cincinnati, PO Box 670592, Cincinnati, OH 45267-0592. E-mail: mutasdf@email. uc.edu. Copyright © 2000 by the American Academy of Dermatology, Inc. 0190-9622/2000/$12.00 + 0 16/2/103582 C onnective tissue disease...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1969
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.130.6.1263